Turn back the clock on ageing skin with maximum-strength 5% Retinol supercharged by Apple Stem Cell technology — for visibly younger-looking skin in weeks.

What It Is

An advanced 5% Retinol serum enriched with Apple Stem Cell extract — a biotech ingredient clinically shown to protect skin stem cells and delay skin ageing at a cellular level. This is Ammuri's highest-strength retinol formula, designed for maximum anti-ageing impact.

What It Does

• Delivers maximum retinol strength (5%) for accelerated skin renewal
• Apple Stem Cells protect skin's own regenerative cells for long-term youthfulness
• Visibly reduces deep wrinkles, fine lines, and crow's feet
• Improves skin firmness, density, and elasticity
• Fades pigmentation, dark spots, and uneven skin tone

Who It's For

For experienced retinol users aged 40+ who want the most powerful at-home anti-ageing treatment available. Ideal for those asking: “What is the strongest retinol serum for mature skin?” or “Does Apple Stem Cell really work for anti-ageing?”

How to Use

Evening only: Apply a pea-sized amount to clean, dry skin 2–3 nights per week. Build frequency gradually. Always apply SPF 30+ the following morning. New to retinol? Start with our 2.5% Retinol Serum.

Pairs Well With

Combine with the Vitamin C Brightening Serum in the morning for a complete day and night anti-ageing routine. Explore the full Anti-Aging Serum Collection.

How to Choose the Right Retinol Strength

Retinol works best when matched to your skin's current experience level. Starting at the right concentration helps you build tolerance gradually and get the most from the ingredient over time.

• Retinol 2.5% — The ideal starting point for retinol beginners and those with sensitive skin. Gentle enough to minimise irritation while still encouraging skin renewal.
• Retinol 3.5% — The natural next step for intermediate users who have built tolerance at lower concentrations. Suited to those targeting more established fine lines and uneven texture.
• Retinol 5% Apple Stem Cell (this product) — Ammuri's most advanced retinol formula. Designed for experienced users seeking maximum skin renewal, combining high-potency retinol with regenerative Apple Stem Cell technology for long-term anti-ageing results.

New to retinol or building up to this strength? Our Beginner Retinol Guide explains the full progression from entry-level to advanced. Browse the complete Ammuri retinol range to find the right formula for where your skin is right now.